ScienceMatrix:Cell Structure & Function can be run either directly from the CD or the computer's hard drive, or even over a network with a building site license.

If you copy it to your hard drive, we suggest you create a folder on your drive called Cell Structure and Function then copy the entire contents of the CD to that folder.

Either way, simply click on the ScienceMatrix icon to launch it.

If you are using Text-to-Speech and do not have the Microsoft SAPI 4 or SAPI 5 speech engine, please see the section on Text-to-Speech to download the software.


Minimum Requirements

ScienceMatrix: Cell Structure & Function requires a system that meets at least these minimum requirements:



ScienceMatrix: Cell Structure & Function does not ship with a license to run on a network. A network license must be purchased from Digital Frog International or one of our distributors.


  • 10 Mb/s network connection or better
  • 100 MB of free hard drive space forScienceMatrix: Cell Structure & Function application and media
    Note: The number of concurrent users will depend on your license and the speed/power of your network setup.

If you encounter problems while running one of Digital Frog International's software titles on your network, please email us for more help.



Make sure your version of QuickTime is up to date
If you launch the program and are prompted to update your version of QuickTime, you must download the latest version. It is available free from Apple at

Text-to-Speech does not work
In order to run the Accessible mode with text-to-speech, you may need to install additional software. For more details, see the section on Text-to-Speech issues.

When I launch the program, I get an error saying QuickTime is required even though I have the latest version of QuickTime already installed.
You may encounter this message when you first launch the program if you have the latest version of QuickTime. We are working on a fix for this. In the meantime, we have a separate page outlining a workaround that allows you to run the program normally.


Windows 98/Me Issues

The Build-a-Cell screen crashes after extended use
Machines running Windows 98 or Windows Me with only 64 MB of RAM installed will sometimes encounter crashes on the Build-a-Cell screen after extended use. Increasing the computer's memory should address this issue.


Windows NT/2000 Issues

Text-to-Speech reads out "..." as "ellipses points".
We will be upgrading the speech engine used by ScienceMatrix and hope to be able to address this in future releases.


If you encounter a problem that isn't covered here, please email or contact us us for more help.



Windows 98, Me, XP, NT, 2000
Some versions of Windows come with text-to-speech drivers pre-installed. However, if you do not have any text-to-speech drivers installed on your Windows 98, NT, 2000, Me or XP system, you can download the SAPI 5.1 drivers here:

Download SAPI 5.1
(52 MB)


If you are using third-party accessibility programs
Text-to-Speech programs such as JAWS should be disabled before running Cell Structure and Function as they will cause conflicts with sound and keyboard controls.

To automate the process of disabling JAWS, download the script “ScienceMatrix.jss”and copy it into the JAWS folder on your hard drive (e.g. c:\JAWS37\settings\env). This will automatically disable JAWS when you launch ScienceMatrix, and re-enable JAWS when you quit.

Download script to disable JAWS with ScienceMatrix.